Mohamed Salah and Roberto Firmino will NOT start Liverpool’s Merseyside Derby at home to Everton on Wednesday night.
The pair have been named on the bench for the clash at Anfield, with Divock Origi and Xherdan Shaqiri coming in.
Elsewhere, Adrian starts in goal after first choice keeper Alisson Becker picked up a red card in their win over Brighton on Saturday and Adam Lallana also starts.
Everton have named an unchanged XI from the team that lost to Leicester on Sunday but Theo Walcott has made a return to the matchday squad.
Liverpool XI: Adrian, Alexander-Arnold, Lovren, Van Dijk, Robertson, Wijnaldum, Milner, Lallana, Shaqiri, Mane, Origi
Subs: Kelleher, Keita, Fabinho, Salah, Gomez, Henderson, Oxlade-Chamberlain
Everton: Pickford, Holgate, Mina, Keane, Sidibe, Digne, Davies, Sigurdsson, Iwobi, Calvert-Lewin, Richarlison
Subs: Lossl, Baines, Schneiderlin, Bernard, Walcott, Tosun, Kean
Mason Greenwood has been handed his first Premier League start for Manchester United’s clash at home to Tottenham.
The striker, 18, has been eased into the first-team this season, making appearances in the Europa League as well as coming off the bench in eleven league matches this season.
But manager Ole Gunnar Solskjaer has given him the nod in a game which sees the Norwegian’s predecessor Jose Mourinho make his Old Trafford return, as he is now Spurs boss.
Man United midfielder Jesse Lingard has also been selected for the starting XI.
As for Spurs, they’ve made two changes from their victory over Bournemouth at the weekend with Harry Winks and Lucas Moura coming in for Eric Dier and Tanguy Ndombele. Christian Eriksen remains on the bench.
Man United XI: De Gea, Wan-Bissaka, Lindelof, Maguire, Young, McTominay, Fred, Lingard, James, Rashford, Greenwood
Subs: Romero, Tuanzebe, Shaw, Williams, Garner, Pereira, Mata
Tottenham XI: Gazzaniga, Aurier, Sanchez, Alderweireld, Vertonghen, Winks, Sissoko, Alli, Son, Lucas, Kane
Subs: Austin, Rose, Foyth, Dier, Ndombele, Eriksen, Lo Celso
Chelsea are also in action and have been handed a huge boost with the return of striker Tammy Abraham for Aston Villa’s visit of Stamford Bridge.
Abraham missed the Blues’ two previous games with injury but has been deemed fit enough to start by Frank Lampard, who will be up against former team-mate John Terry, who is the Villans’ assistant manager.
Chelsea XI: Kepa, James, Zouma, Christensen, Azpilicueta, Kovacic, Kante, Mount, Willian, Abraham, Pulisic
Subs: Caballero, Tomori, Emerson, Jorginho, Hudson-Odoi, Batshuayi, Giroud
Aston Villa XI: Heaton, Elmohamady, Konsa, Mings, Targett, Marvelous, McGinn, Hourihane, Trezeguet, Wesley, Grealish
Subs: Nyland, Engels, Taylor, Douglas Luiz, Lansbury, Jota, Kodija
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Below are the other matches in the top flight on Wednesday night.
Leicester vs Watford
Southampton vs Norwich
Wolves vs West Ham